Friday, 11 February 2022

Fever with Pancytopenia , MEGALOBLASTIC ANEMIA

  Gen med case presentation;

Feb 11,2022

Name;Ramya reddy pebbeti.

 Roll no;105 .

This is online E log book to discuss our patient’s de-identified health data shared after taking his/her/guardian’s signed informed consent. Here we discuss our individual patient’s problems through series of inputs from available global online community of experts with an aim to solve those patients’ clinical problems with collective current best evidence-based inputs. This e-log book also reflects my patient centred online learning portfolio and your valuable inputs on comment box is welcome. 

 I’ve been given this case to solve in an attempt to understand the topic of “patient clinical data analysis" to develop my competency in reading and comprehending clinical data including history, clinical findings, investigations, and come up with diagnosis and treatment plan

Following is the view of my case :

CASE PRESENTATION ;
DOA:10/02/22

chief compliants;

 He is a 23 yr old male who is a auto driver by occupation came to the opd yesterday with complaints of ;
Yellowish discoloration of eyes since 15 days
Fever - high grade since 1 week
Abdominal discomfort since 1 week
SOB since 1 week 
Blood in stools and burning sensation while passing stools 2 episodes  2 days back

3 years back;

He was apparently asymptomatic 3 yrs back then he got fever for which he went to the hospital where he is found to have pallor and Hb levels were 4gm% for which he received 3 PRBC transfusions and there only they diagnosed him as B12 deficiency anemia for which he received b12 injections and his Hb levels increased to 12gm%. 

Now;

 He noticed yellowish discoloration of eyes since 15 days and fever , abdominal discomfort  (squeezing type)since 1 week for which he went to hospital and received medications and he also took herbal medicine for jaundice

Personal history;
Diet; mixed
Appetite; reduced
Bowel and bladder: regular
Sleep: adequate
He takes beer (2 bottles) twice weekly
 
General examination;
He is conscious, coherent, cooperative and we'll oriented to time,place,person
Vitals ; 
Temp; febrile
PR;80bpm
RR;20cpm
Bp; 110/80 mm ofHg
SPO2; 99%
 



Pallor and icterus; present
Cyanosis, clubbing, lymphadenopathy-absent
Oedema; upto ankles on both legs
Hyperpigmentation of knuckles is present

Systemic examination;
 
Per abdomen;
Soft and non tender
No scars ,sinuses  and engorged veins

Respiratory system;
BAE+

CVS;
S1,S2 HEARD ,jvp raised and flow murmur

CNS : intact
 
Investigations;

Reticulocyte count;


Hemogram;


LFT;


RFT;


USG ABDOMEN;


2D ECHO;


LDH;


Provisional Diagnosis;
 Fever with Pancytopenia
?megaloblastic anemia

Treatment;

On 10/02/22;

Inj methylcobalamin 1500 micrograma in 100 mlNS iv/oD
Inj.lasix 40 mg BD
Inj.pantop 40 mg iv/oD
Inj.zofer 4 mg iv/OD
Tab.ultracet BD
Tab.PCM 500 mg PO
I/O charting


On 11/02/22; 
Hemogram;
Hb;3.1 gm%
TLC;3200
PCV;9.1vol%
MCH;33.7
RDW-cv:31.5
RBC;0.92 million/cumm
Platelet;28000/cumm


LFT;
TB;8.04mg/ dl
DB;0.64
AST;61
ALT;17
ALP;72
TP;6.2
ALBUMIN;4.19
A/G ratio;2.08

Serum ferritin;156ng/ml

ESR;30mm-1st hr

Same treatment 

Investigations and treatment on 13/2/22;

Hemogram ;
Hb;3.2 g/dl
TLC;4400
PCV;8.9 vol%
MCV;99.4
MCH;35.1
MCHC;35.3
RDW-cv;32.6
Platelet;35000/cumm
RBC;0.90millions/cumm

LFT;
TB;1.84
DB;0.30
AST;50
ALT:13
ALP;65
TP:5.8
Albumin:3.78
A/G RATIO;1.87

No fresh complaints.

Treatment;
Same treatment

 On 14/02/22;
He c/o 1 episode of blood in stools for which he is referred to general surgery dept.

Surgery referral;

Treatment ; same treatment along with
        #  High fibre diet
        #Adequate hydration
       #Sitz bath for 20 min TID
      #Oint.lignocaine for LA/ Bd
      #Tab.oxerute-cD /OD/2 days

On 15/02/22; and 16/02/22;
Same treatment

On 17/02/22 
Hb;5.9
TLc;3700
pLT;1.5 lakhs
 
And also same treatment


Monday, 7 February 2022

HYPOGLYCEMIA ,? DIABETIC NEPHROPATHY

 Gen med case presentation;

Feb 7,2022

Name;Ramya reddy pebbeti.

 Roll no;105 .

This is online E log book to discuss our patient’s de-identified health data shared after taking his/her/guardian’s signed informed consent. Here we discuss our individual patient’s problems through series of inputs from available global online community of experts with an aim to solve those patients’ clinical problems with collective current best evidence-based inputs. This e-log book also reflects my patient centred online learning portfolio and your valuable inputs on comment box is welcome. 

 I’ve been given this case to solve in an attempt to understand the topic of “patient clinical data analysis" to develop my competency in reading and comprehending clinical data including history, clinical findings, investigations, and come up with diagnosis and treatment plan

Following is the view of my case :

CASE PRESENTATION ;
DOA:05/02/22

chief compliants:  A 65 yr old female ,Home maker came  to the casuality on 5/02/22  with complaints of altered sensorium since 2 hrs .
 She was apparently asymptomatic 3 yrs back 
3 yrs back due to back pai and B/L knee pain pt used NSAIDS and herbal medication for pain relief.(intermittent use)
45 days back she had thorn injury in left leg for which she went to local hospital for non healing status of injury ,there she diagnosed with DM and HTN  ( on medication )
4 days back she went for regular checkup where her creatinine levels were found to be high.
Now she c/o altered sensorium since 2 hrs,sob at rest  since  1 day and also vomitings and decreased urine output .

Personal history;
Diet :mixed
Appetite; normal
Bladder; reduced output
Sleep : adequate
No addictions
 
General examination;
She is c/c/c
Pallor  - present
Icterus, clubbing, lymphadenopathy- absent
Oedema - present
Vitals ;
Temp; afebrile
PR;90bpm
BP;200/120 mm hg
RR;22 cpm
SPO2; 99.6 at RA

 


Systemic examination;
RS: BAE+
CVS ; S1 ,S2 HEARD 
CNS ; NAD

Investigations;
CBP;
Hb- 9.0 
TLC-7800
PLATELETS-1.73
RBC-NC,NC

RFT;
Urea;139
Creatinine;5.7
Na+;137
K+;5.1
Cl;102
Serology - negative

LFT;
TB;0.45
DB;0.16
AST;38
ALT;27
ALP;210
TP;5.4
A/G RATIO;1.36
Albumin;3.11

USG;


2D ECHO ;


ECG;





Provisional diagnosis;
Hypoglycemia secondary to OHA,
?DIABETIC NEPHROPATHY
? NSAID INDUCED NEPHROPATHY

Treatment;
On 5/2/22:

Inj.10 D infusion to maintain Grbs 150-200 mg/dl
Hourly Grbs monitoring
Inj.lasix 40mg iv/bd
Inj.pan 40 mg iv/OD
Inj.optineuron 1 amp in 100 ml NS iv/OD

On 6/2/22:
GRBS monitoring hourly
Inj.10 D infusion
Inj.lasix 40 mg iv/ bd
Tab.Amlong 10 mg po/OD
Inj.pan 40 mg iv/oD
Inj optineuron 1 amp in 100 ml NS iv/ OD

On 7/2/22 :
GRBS monitoring 2 hourly
Inj.pan 40 mg iv/OD
Inj.optinueron  1 amp in 100 ml NS IV/OD
Tab. Amlong 10 mg po/OD 
Tab .nicardia 20 mg po/ TID